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Thus, although TKI-induced imbalance between the BCL-2 family proteins was necessary for apoptosis, it was not sufficient for the completion of this cell death, suggesting the inhibition of other antiapoptotic signals activated by BCR-ABL.
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The SNP genotyping was performed after completion of the cell migration assays, in order to minimize subjective influence on the interpretation of the migration assay results.
Furthermore, we show that down regulation of PrPc expression in Caco-2/TC7 enterocytes lead to a complex pattern of alterations in both cell architecture and completion of the cell division process.
After completion of the cell lineages (about 8 hours later at 18°C), the notum was dissected out and immuno-labelling with specific markers was performed to confirm the information obtained by in vivo observations.
We identified new genes involved in DNA metabolism, completion of the cell cycle, and morphogenesis.
Additionally, cyclins B1 and D1 have been shown to be essential for successful completion of the cell cycle.
Activated FOXM1 binds to the DREAM transcription factor complex necessary for completion of the cell cycle [ 46].
In addition, 249 F-box transcripts showed preferential accumulation in pollen following completion of the cell cycle (Table 1).
We observed an increase in SLX4 SUMOylation levels as the cells progressed through the S and G2 phases, decreasing again upon completion of the cell cycle when the cells re-entered the G1 phase.
The presence of labile residual cell attachments suggests a delay in completion of cell division and redistribution of cell patches following cytokinesis.
Nek-1 may thus be a more general regulator of the apicomplexan cell cycle, which is only upregulated in microgametocytes due to the rapid completion of multiple cell cycles at this life cycle stage.
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