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All subjects were given the special tubes and phlebotomy supplies to submit various blood and breast milk samples and contacted on a regular basis for the completion of the sampling.
On day 7, after the completion of the sampling for the 48 h post-dose plasma apremilast concentration determination, oral doses of rifampicin 600 mg once daily were administered for 15 days (days 7 21).
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Evaluation / Assessment: Students will be evaluated based on participation in the initial task and subsequent class discussion, contribution to small group discussion, and thoughtful completion of the sample home page.
The first GPs randomly listed (considering region, practice setting and gender) were asked to participate in the research until completion of the sample.
Five months after completion of the sample collection, and in order to evaluate intraobserver agreement, a second measurement process was performed both qualitatively and quantitatively using an anthropometer.
Therefore, the questionnaire was administered to all women that met the inclusion criteria (i.e., 32 weeks of gestational age and two or more antenatal care visits) in both clinics' groups until completion of the sample size.
After completion of the field sampling and analyses of the samples from the original 12 cities, the data set was not equally populated (25% per cell), but heavy on the non-smoking home/nonsmoking workplace data (Cell 4) with 686 (57%) subjects, and light on the smoking home/smoking workplace (Cell 1) with only 136 subjects (11%).
A structured questionnaire was administered at household level immediately after the completion of the air sampling to collect fuel use related data and events that occurred at the time of NO2 sampling.
After completion of the pharmacokinetic sampling, treatment continued with rubitecan given orally at a dose of 1.5 mg/m2/day, to be increased up to 2.0 mg/m2/day, under fasting conditions for 5 consecutive days per week until disease progression.
When GCF sample was collected using the modified GCF collecting device (made of black polyester films), a colour change from white to black was observed, hence confirming the completion of the GCF sampling process.
Following completion of the GCF sampling, patients were randomly assigned to CHX or placebo groups by taking into account the gender, age and the extent of the gingivitis by an independent periodontist who kept the allocation information confident until the data collection and biochemical analysis were completed.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com