The next challenge – sequence completion and verification – requires the closing of the gaps between contigs, isolation and characterization of centromeric and telomeric regions that are poorly represented in libraries, and verification of contig assembly.
About a decade after completion of the M.B.A. course, the gap in hours worked adds up to the cumulative equivalent of a six-month difference in job experience between men and women, and the difference is a costly one, the report says.
Monthly environmental inspections of MHM supportive infrastructure were conducted at the onset and completion of the project to identify design gaps and areas for improvement, such as examining toilet facilities, washing facilities, and disposal systems at both the household and facility levels.
To this day, Washington University continues to contribute to the completion of the human genome, by filling in the gaps and monitoring and including all of the new content.
If nad6 is found in this gap upon completion of the S. nux mtDNA sequence, S. nux would share the nad4- nad6 boundary with A. vastus.
For the gaps that remained in the mitochondrial genomes after using the pulmonate-specific primers and shotgun sequencing, individual-specific primers were designed and the gaps were primer-walked until completion of the genome (Additional file 1).
Here's a simple example of a hurdle that leads to unnecessary complications -- a gap between the completion of the transaction and the receiving of the product itself.
The months-long gap between the completion of the production and release meant Alan Dean Foster was allowed to watch the whole film before writing the novelization, although the novel would contain scenes absent from the final edit.
Despite the tremendous efforts and successful completion of the Human Genome Project by April 14th 2003, a set of recalcitrant gaps remain in the euchromatic part of the final human genome sequence.
(The sequencing of the O157 H7 genome is nearly complete; only two gaps remain). We should view with scepticism press releases announcing the completion of a genome sequence in a day15 — they refer simply to the completion of the initial sequencing part of a project, but many gaps (frequently hundreds) always remain.
