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The plasma volume was measured at 15 and 60 min after completion of the fluid resuscitation.
The plasma volume was measured again at 15 min and at 60 min after the completion of the fluid resuscitation.
In these cases, both parents and teachers were involved in the completion of the fluid record.
Yet, the selection bias in this study was even reduced by the fact that the completion of the fluid diary was integrated in the school activities.
In Belgium, China and Iran, the completion of the fluid diary was done by the teachers in the school and by the parents at home, whereas in the rest of the countries, the diary was filled by main caretaker (mums).
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Although this fluid regime was arbitrarily chosen, it was based on the peak increase in intravascular volume with lactated crystalloid solution occurring immediately after completion of the rapid fluid infusion [ 36, 37] and the low clinical risk of crystalloid solution [ 22, 38].
Whether the PPV value obtained at completion of such fluid load in such a patient may be used as the 'operational' threshold for the following hours of management, provided that other major determinants of PPV (IAP and tidal volume) are kept constant, can be reasonably hypothesized but deserves further validation.
Besides an introduction with instruction on the completion of the record, the 7-day fluid record consisted of blank tables, one for each day.
Clinicians would have to wait almost 30 years, until the completion of the landmark Saline versus Albumin Fluid Evaluation (SAFE) trial, to begin to draw definitive conclusions.
Upon completion of the fracking process, the direction of fluid flow reverses, with a proportion of the injected fluid returning to the surface.
After the completion of the 60 minute trial of fluids routine care will follow as directed by the treating clinician.
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