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Altogether these data indicated that during mitosis HG-EOC cells expressing p53MUT accumulate a significantly higher amount of damaged DNA and that, in this setting, stathmin expression is necessary for the proper completion of M phase.
Noteworthy also is the observation that phospho(S807/811 -Rb (pRb), which is phosphorylated at the G1 to S transition [ 46] and dephosphorylated at the completion of M [ 47], is elevated with RT.
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Our data show that timely completion of M-phase requires proteolysis-independent control of MPF activity.
We then construct the set of completions of M.
A supervaluation of M is a partial assignment of truth-values to formulas that makes a formula true if all completions of M make it true, false if they all make it false, and truth-valueless if they disagree.
In contrast, Tim depletion prevented the progression and completion of normal M phase events, resulting in defects in microtubule organization, chromosome condensation, sister-chromatid cohesion, and formation of lagging chromosomes (Fig. 3).
In other words, the dephosphorylation of pEndos by PP2A-B55 is an absolute requirement for rapid completion of the M phase-to-interphase transition.
The route was turned back to local control in October 2002 by the Michigan Department of Transportation MDOTT) after the completion of M-217 (Michiana Parkway).
Let H m ( R n ) be the completion of C 0 m ( R n ) with respect to the norm ∥ f ∥ m 2 = ∑ | q | ≤ m ∫ R n | D x q f ( x ) | 2 d x.
On completion of solubilization, 0.2 M HCl in 1.5 m Tris-HCl (200 µl) was added to each well.
The expected date of completion for M-231 is set for sometime in 2016 pending funding availability.
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