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To fully confirm this effect will require completion of larger simulations with wider initial reconnection fronts.
These studies are generally small sized and this feature has called attention to the need to summarize the individual results, while waiting for the completion of larger studies, designed to answer questions that have been raised by preliminary studies.
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Although the available experimental information about interactomes is not as complete and as accurate as the one on genomes, the recent completion of large protein interaction studies has offered an unprecedented amount of information about the protein web shaping cell organization [ 5- 7].
Over the past 30 years, the biomedical model displaced the psychoanalytic one, bolstered by advances in pharmacology, modern genetic and neurological research and the completion of large-scale empirical studies that concluded that psychoanalysis was useless at best and actively destructive at worst.
Monthly data collected between 1990 and 1996 shows that both E. coli count and BMWP score improved following flushing of the foul sewerage system in 1992, but that only E. coli count improved following the subsequent completion of large-scale remedial engineering works.
Although confirmation of the efficacy of this pharmacological approach awaits completion of large clinical trials, the adjuvant use of these compounds is common in patients that do not meet targeted reductions of lipoproteins while taking statins [6] [10].
The sub-cloning protocol can hasten the completion of large projects through parallel lines of construction in multiple vectors that are progressively joined together until the final combination is attained.
Ultimately, answering this question will require completion of large-scale controlled clinical trials.
The completion of large genome-wide association studies introduced single nucleotide polymorphisms (SNPs) as risk factors for human disease.
As a consequence, completion of large assemblies (e.g., the 1- to 2-Mb dot chromosome of a given species) generally stretches over 2 3 yr.
Its efficacy for treating acute mania was recently reconfirmed following the completion of large-scale, randomized, placebo-controlled trials in North America using extended-release CBZ [ 12, 13].
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