Pattern completion, the ability to retrieve complete memories on the basis of incomplete sets of cues, is a crucial function of biological memory systems.
Pattern completion, the ability to retrieve complete memories initiated by partial cues, is a critical feature of the memory process.
Pattern completion, the ability to retrieve complete memories initiated by subsets of external cues, has been a major focus of many computation models.
The study investigates how children with autism process different types of memories by examining brain region activity and connectivity during the completion of memory tasks.
If the NMDA receptor (especially in CA3) were to play an essential role in pattern completion during memory retrieval, one should expect the forebrain knockout mice to exhibit much more profound memory retrieval deficits than that of CA3-specific NMDA knockout mice.
Significant deterioration was seen over the follow-up period in three of nine sub-tests: object assembly, picture completion and memory for designs.
Currently, little is known about the actual molecular and cellular mechanisms underlying the pattern completion of memory recall.
This latter REM latency association alone did not, however, differentiate whether it is the time to achieve REM following the onset of sleep, or the time it takes to achieve REM sleep following the completion of memory encoding, which includes time spent awake prior to the onset of sleep.
To re-examine the role of NMDA receptors in pattern completions during memory retrieval, we set out to apply inducible and region-specific gene knockout methods that would allow us to restrict the NMDA receptor knockout to the recall phase.
Thus, our genetic analyses suggest that the NMDA receptor is not required for pattern completion during associative memory recall.
Therefore, our results reveal that a delicate control of the brain's dopamine level is critical for pattern completion during associative memory recall.
