We assessed therapists' adherence to the protocol by completion of a treatment log.
The SQ-standardized grass allergy immunotherapy tablet (AIT) has been demonstrated as a disease-modifying treatment which gives a sustained effect even after completion of a treatment course.
On completion of a treatment cycle, seedlings were kept overnight at 30 °C and the same series of treatments was then repeated to establish any changes in the expression pattern compared with the previous day's exposure to the same stress.
A cure was defined as both the completion of a planned treatment and the negativity of two consecutive cultures, whereas a treatment completion was considered as the former alone.
MTB or MK treatment success was comprised of a cure and a treatment completion.
Neither arm demonstrated a treatment completion rate statistically greater than 60%, which was the predefined feasibility criterion.
Both arms just failed to meet the predefined feasibility criterion of a treatment completion rate statistically greater than 60% (arm A 71%, 90% CI 58 81%, P=0.079; arm B 67%, 90% CI 55 78%, P=0.184).
A more recent outpatient trial of Zipfel et al. [ 32] also reported a treatment completion rate of 74% but Schmidt et al. [ 33] reported that only 25% participants completed the majority (>61%) of sessions.
Even after completion of treatment, a significant proportion of patients sustain disability from nerve damage, requiring continued (self-) care to limit further secondary damage (5).
Our data are in line with previous studies reporting that many PCPs considered ADs as effective and sufficient in most cases and psychotherapy as a completion of treatment [ 15, 20].
