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When the breakdown occurs, the server is unable to render service to the customers, but after completing repair provided by a repairman, it works as efficiently as before the failure.
For example, poly(ADP-ribose) polymerase 1 (plays) plays a crucial role in multiple repair pathways, including BER, in sensing damage and initiating and completing repair of DNA lesions and DNA strand breaks.
Ku80 substantially protects the breaks [ 10] allowing subsequent intervention by PKcs [ 11] which, in turn, appears to be vital for the recruitment of the XRCC4/ligase IV proteins to religate DNA breaks thus completing repair [ 8, 12, 13].
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Crews were completing repairs after the first break, which was reported at 4 30 p.m. Monday, and had started reopening traffic lanes at 3 40 a.m.
"The crews worked nonstop for almost 70 hours and were able to complete repair work on the damaged eyebar," said Randy Iwasaki, director of the California Department of Transportation.
This is followed by a homologous recombination step to provide the genetic information needed to complete repair.
Finally, the LIG4 XRCC4 complex in vivo carries out the ligation step to complete repair [ 10].
We analyzed the incorporation of one or two nucleotides and the ability to complete repair (see figure legend and Fig. S1C).
The completed repairs to date represent 65 percent of those needed under the recalls, which were begun in November and January.
The new contractor is ACS State and Local Government Solutions, which expects to complete repairs on the lane equipment over a three-month period, Mr. Rasmussen said.
The power is working in most of the city, though with intermittent outages, and work is under way to complete repairs to the water system.
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