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In stage 1 we assessed the reliability and completeness of the clinical study reports.
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The analysis of data in order to reproduce the findings of the clinical studies (where possible) provides both a check to the accuracy of receipt and completeness of the data.
Another limitation of our study is that we looked only at inconsistencies in and completeness of reporting; we did not meta-analyse the clinical study report data to see whether the results were different from meta-analyses based on publicly available data only, but we plan to do this in a larger sample of trials.
The accuracy and completeness of the clinical phenotype identified in this study is entirely dependent on the clinical information that was documented in the medical records of these subjects, often before the NRXN1 deletions were identified in them.
To aid us in determining completeness of the relevant parts of clinical study reports we constructed an extraction form based on the CONSORT statement checklist (see web extra).
Private prison operators disputed the accuracy and completeness of the study.
This contributed to the inclusiveness and completeness of the study.
We include A. thaliana for enhancing the completeness of the study.
Review of bibliographies of papers was also carried out to ensure completeness of inclusion of all relevant clinical studies.
Water is added and examined for completeness of the studies.
Similarly the accuracy of comorbid diagnoses, and the completeness of clinical measurements will be subject to routine clinical variation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com