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We also excluded temporary residents and patients with fewer than 6 years of medical records before the index date to ensure completeness of exposure data.
The standard WSDOH questionnaire was supplemented with an additional set of questions to ensure completeness of exposure data collection and to better align Washington data with New York data.
To ensure completeness of exposure data we also excluded temporary residents and patients with fewer than 6 years of medical records before the index date for the main analysis - and fewer than 10 years for the further analysis.
To this end, INWORKS was not intended to assemble the largest number of nuclear workers possible, but rather to assemble those cohorts that were most informative with regard to quality and completeness of exposure and follow-up data.
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Balance test results for up to 6915 children were available for analyses, depending on the completeness of the alcohol exposure data.
These decisions involve tradeoffs between the accuracy and precision of exposure measures, the completeness of the exposure assessment, and the statistical power of the study, as well as the resources available and burden that will be placed on participants.
The strengths of this study include the population-based design, with minimal selection bias; the high quality and completeness of the data on exposures (length of residence and country of birth); and the ability to distinguish between the modes of labor onset.
The AHS has several strengths, including a prospective design, comprehensive pesticide exposure assessment, completeness of follow-up, and high participation rates.
Whether such trends reflect differences in case definition or completeness of reporting across registries and exposure categories, and whether these may have led to important biases, is difficult to establish with any certainty.
Major strengths of the current study include the use of nationwide prospectively recorded data, completeness of follow-up, and use of validated measures of exposure and outcome.
Use of a population-based prescription registry, whose completeness approaches 100% (Gaist et al, 1997), ensured unbiased assessment of exposure before CRC diagnosis and eliminated recall bias.
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