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Tim Carmody, a blogger at Wired, described the project as "completely problematic" and sounding like "something out of a darkly satirical science-fiction dystopia".
Not surprisingly, the definition is completely problematic.
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This imputation-based filtering did not completely eliminate problematic SNPs with poor genotype clustering, as determined by visual inspection (results not shown).
This will completely uninstall the problematic program from your computer.
All are problematic.
This is why it is rather problematic to completely eliminate glutamate from the diet.
The fact that the Sykes-Picot agreement effectively created new countries - including the modern states of Iraq, Jordan, Lebanon and Syria - without the consent or participation of anyone living in the region, is both morally problematic and completely contrary to today's international relations norms, which are governed - or at least should be governed - by international law.
Simulations performed by us suggest that the problem could be solved by completely standardizing the potentially problematic explanatory variable.
It removes stubs of proteins left behind on the surface of nerve cells and is needed to make other proteins, so completely blocking it would be problematic.
"It becomes problematic when you completely rely on that [feedback system]," Flores said.
Although not an agricultural threat, its presence can be very difficult to completely eradicate, and is especially problematic in overgrazed pastures.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com