Sentence examples for completely knockout from inspiring English sources

Further efforts to completely knockout Dnmt2 may be able to provide solid evidence on the functionality of Dnmt2.

The mdr-1a/b (Abcb1a/b) double knockout completely eliminates mdr-1-mediated mdr-1-mediated mdr-1-mediated.

In clear contrast, Bax knockout completely abrogated TRAIL- and TRAIL/wortmannin-induced apoptosis.

This result is not completely surprising since knockout data is considered one of the most informative data for inferring regulatory relationships (Marbach et al., 2012).

A second study by Kolesnikov et al. (2011) examined scotopic OKR when rod pathway function was severely reduced but not completely eliminated (Gngt1 knockout).

In the mouse MI model exploited in the present study, O β knockout completely abrogated protective effects of OSM following operation, which further confirmed that OSM exerted its angiogenic function in MI mice through and merely through type II receptor.

These data are consistent with the fact that neither β2 nor α4 knockout completely abolishes the entire extracellular domain of the β2 nAChR subunit that is specifically recognized by mAb295 [4,25].

Thus, although these nAChR subunit knockouts completely eliminate nicotinic agonist binding sites and functional nAChRs, a small amount of a non-functional protein appears to be produced that is able to form some complexes with interacting proteins.

Encouraged by these observations, Negishi and coworkers provided further mechanistic evidence suggesting ERK is an endogenous signal, regulating CAR phosphorylation and nuclear translocation, by which U0126-mediated Cyp2b10 induction via ERK1/2 deactivation was completely abrogated in CAR knockout mice (Koike et al., 2007).

Only rare swellings were observed in cortical neuronal cultures from homozygous knockout mice, completely lacking spastin (SpastΔE7 and SpastΔE5-7) (20 20).

3) It is difficult to tell whether the D1R knockout mice completely lack FAA or whether it is merely attenuated.