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"It's completely indispensable".
Matatus are both notoriously reckless and completely indispensable.
Smoking ruins his sense of smell, a sense he finds completely indispensable for hunting.
No one wants to admit that doing your job competently doesn't make you completely indispensable and irreplaceable.
It is easy to rise up the office ranks, making yourself completely indispensable as a result, by just googling the coffee machine manual and learning how to turn it off and on.
Thus, neither arginine side chain is completely indispensable for binding, but each is required for high-affinity binding.
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The completely conserved residues indispensable for DNA-binding are indicated by middle dot.
All are indispensable.
A good deal of interesting information is hidden around the site, not least the indispensable but completely unsearchable Hansard record of debates in the Commons and the Lords.
Enzymatic activity of CK-B was indispensable since cyclocreatine completely blocked the gain in migration capacity in both CK-B expressing cell pools (Figure 6C and D, Video S3) without overt effects on viability or proliferation rate (Figure S1).
In this case essential metabolites cannot be derived from imported precursors, but rather need to be completely synthesized, making additional reactions indispensable.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com