Sentence examples for completely impaired from inspiring English sources

Thus, binding of drug is completely impaired leading to complete drug resistance (18, 33).

They have argued that Mr. Malvo voluntarily chose to be with Mr. Muhammad, that the so-called indoctrination lasted just a few weeks and could not have completely impaired his faculties and that he was predisposed toward antisocial behavior.

Importantly, while target antigen affinity was completely impaired, CD3 binding affinity was conserved in each molecule.

The mechanical stability of the joints is completely impaired to 15 weeks of ageing (post-ageing cluster), when the effect of the oxides predominates compared with the interlocking.

The ABA-activated phosphorylation of AREB/ABFs was completely impaired in the SnRK2 triple mutant, srk2d srk2e srk2i (Fujii et al. 2009; Fujii & Zhu 2009).

Consistent with our hypothesis, NF-κB was potently activated by doxorubicin in control cells, but completely impaired in Malt1-deficient cells (Fig. 1A).

The gamma-irradiation by doses greater than 3 Gy completely impairs the resistance to infection and causes a disbalance of cytokine production in mice.

However our finding that vaccinia with an intact B18R gene is still enhanced by TSA suggests that either the anti-interferon activities of B18R are insufficient to completely impair the cellular interferon response or alternatively the effects of TSA go beyond interferon induced anti-viral responses.

These results suggest that IKKβ-KM overexpression was not able to completely impair endogenous IKKβ function.

Finally, we also recorded the presence of intestinal parasites, as these are known to grow to such a large size as to partially or completely impair gonad development in R. argentea (Cowx et al. 2008).

14 However, RXR activation only partially recovered myelin debris phagocytosis and RXR inhibition did not completely impair remyelination in young subjects, suggesting that other factors, such as modulation of specific binding partners of RXR, may be playing a role in myelin debris clearance.