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Before a cell can divide, it must accurately and completely duplicate the genetic information encoded in its DNA in order for its progeny cells to function and survive.
Such costs would include enough processing power to completely duplicate the original computing.
Thus, the adiponectin used in this system may not completely duplicate the effect of native glycosylated adiponectin under physiological conditions.
Telomere erosion is a consequence of a variety of factors that include the inability of the replicative polymerase to completely duplicate linear DNA (also called 'end replication problem'), postreplicative processing of chromosome ends, and sporadic telomere attrition due to repair events at damaged telomeres (Lansdorp, 2005).
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If the four lecticans arose as a result of the alleged two rounds of the whole-genome duplication early in vertebrate history, the fact that the family was also completely duplicated in fish and retained after the duplication appears very non-random and implies some functional explanation.
Factors that contribute to progressive telomere erosion include the inability of the replicative polymerase to completely duplicate linear chromosomes (the end replication problem), nucleolytic processing of telomeric ends, and sporadic telomere attrition due to defective telomere maintenance and repair mechanisms.
Clinical features of ADLD patients were similar in all patients in whom LMNB1 was the only gene completely duplicated, and we did not notice differences associated with different duplication extents.
Based on a similar approach to that used in the present study, the authors showed that none of the three rounds of genome duplication in the vertebrate lineage (1R/2R/FSGD) led to a completely duplicated glycolytic pathway in extant genomes.
The sequenced fosmid is completely duplicated, but subtle, single nucleotide differences between the proximal and distal duplications are consistent with the clone actually spanning the inversion breakpoint.
DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated.
The spectral evolution was completely duplicated with the irradiation of anthracene embedded in KCl or NaCl.
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