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This sequence conservation includes two characteristically-spaced, completely conserved cysteine residues (asterisks, Fig. 1b).
For the CHD-ZW-common probe, all species listed were completely conserved.
The catalytically important amino-acid residues determined in GHF2 enzymes were completely conserved in AkMnsd.
For example, at most 0.6% of the positions were completely conserved when the mammalian substitution rate was 2.2 × 10−9 per base per year71 (Supplementary Fig. 12).
This maximized our chances of sampling pathogenic alleles, because completely conserved positions are rare when species sampling is diverse and evolution is strictly neutral.
The fraction of sites with identical base across all 58 species, which would appear to be completely conserved in a sequence alignment, was determined from the datasets generated.
Such spurious variants would also be likely to appear among A. kamchatica variants even if the corresponding regions were completely conserved between A. kamchatica and its parents.
The completely conserved residues indispensable for DNA-binding are indicated by middle dot.
P27 and P77 were found to be completely conserved.
This residue is also completely conserved among all the MoLFunCs.
This residue is completely conserved among the MoLFunCs.
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