Sentence examples for completely abrogates from inspiring English sources

We also show that chemical deacylation of LAM completely abrogates its association with the supported lipid bilayers.

Both Tyr260 and the neighboring Arg261, mutation of which completely abrogates activity12, are also very highly conserved (Supplementary Fig. 4) and form multiple noncovalent interactions that further serve to orient both reentrant active site loops (Fig. 2c, d).

However, mutation of both Ser12 and Ser13 residues to Ala in Delta1-317 completely abrogates activity, while individual substitutions have no effect.

Disruption of either lasR or lasI completely abrogates the expression of ambBCDE and the production of IQS (Lee et al., 2013) (Fig. 3).

We show that mutagenesis of the N-terminal KRIT1 NPXY amino acid sequence, a motif critical for ICAP-1 binding to beta1 integrin molecules, completely abrogates the KRIT1/ICAP-1 interaction.

It has been reported previously that limited protease treatment of Pf-iRBC with chymotrypsin almost completely abrogates NPP activity [20].

Also, mutating 2 of these residues to alanines completely abrogates MHV-68 infectivity (L. Gillet and P.G.

Mutation of these sites completely abrogates the ability of PKA to phosphorylate and regulate activity of Gli3 [16].

Pharmacologic inhibition of ASM by imipramine completely abrogates the induction of MMP-1 upon TNF or IL-1β.

Support for the need for caspase-1 encapsulation derives from our finding that mechanical disruption of microvesicles completely abrogates their apoptotic potential.

Nicotinamide partly or completely abrogates yeast lifespan extension by CR, possibly by increasing cellular levels of NADH, a competitive inhibitor of the Sir2 protein [41], [42].