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All patients completed sleep and medication logs for 2 weeks prior to the sleep apnea/PSG recordings.
Two weeks prior to the experiment, participants completed sleep diaries, had an adaptation night in the sleep laboratory and wore actigraphs in order to verify adherence to a regular sleep-wake schedule.
Ten of the 14 (71%) who dropped out completed sleep measurements and six (43%) completed adiposity measurements.
Participants completed sleep diaries each morning for one week prior to starting the experimental agent and during the last week of the study (days 21 to 28).
All participants completed sleep diaries detailing their bedtime, wake time and sleep quality, and 88 subjects also wore electronic sleep monitors known as actigraphs.
At one year 49 patients had completed sleep and adiposity follow-up measures, and 44 had completed the one year treatment (see appendix 1 on bmj.com).
Similar(50)
During the four week protocol, the volunteers completed sleep-activity logs daily.
During the baseline (placebo) week, the volunteer completed sleep-activity logs daily and continuously wore an Actillume to monitor baseline sleep-wake patterns and baseline illumination patterns.
To do this, we use actiwatches – small accelerometers worn on the wrist that record how much people have moved, which is a proxy for when they're active and not active – and ask all our participants to complete sleep diaries.
To have restful sleep, each phase of sleep must be completed; otherwise, sleep disruption will result.
During the last 10 weeks of the study, patients will be assessed with the MDI twice and every 2 weeks fill out VAS regarding anxiety, fatigue, pain, general well-being and sleep, complete a sleep diary and fill out the KSS.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com