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This was completed on observations for untreated cells, EGF, IGF1, IL6, TNFα, DHT, and docetaxel treated cells using all three time points (30 minutes, 4 hours, and 24 hours).
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PORTAAL observations are completed on an observation log (see https://sites.google.com/site/uwbioedresgroup/research/portaal-resources) that asks observers to record the timing, frequency, and presence/absence of events as they occur in an activity.
Two participants dropped out on day 7 without explanation, but they received treatment and also completed one time point observation.
This decision was based on the fact that psychomotor activity can fluctuate over time and the DI was completed based on observations over a seven-hour period.
The observation tool was completed on a real time basis by one trained study observer who was not a member of staff (BG) seated in the courtyard in a visible non-obtrusive position with line-of-sight to all parts of the courtyard.
The observations were completed on the 15th of December 2007.
A total of 20 h of observation were completed, on average 30 min per technology.
The study started on 2 November 2006; inclusion of patients concluded on 28 February 2007, and observation was completed on 27 December 2007 [ 32].
The study started on 2 November 2006; inclusion of patients concluded on 28 February 2007, and observation was completed on 27 December 2007.
Observations sessions were completed on 34 and 35 occasions in the SR and OP ICUs respectively including 277 and 418 HH opportunities.
Recording observations has often been completed on a physical paper note pad with a pencil, however times are changing.
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