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In order to classify and complete the functional characterization of the human proteome, many of the unknown proteins are usually inferred from their counterparts in other species.
The two key genes that complete the functional subnetwork among these gene pairs, the glycoproteins FN1 and SPARC, are bona fide markers of EMT [ 63, 64].
Two subjects with SCI were unable to complete the functional MRI scan because of technical problems related to the stimulation equipment and were therefore excluded from further analysis.
> -wrap-foot> To complete the functional annotation of cancer genes, we derived expression levels for 1528 of them from two high-throughput gene expression experiments on 109 human tissues (99, 100).
Additionally, chemical mutagenesis particularly in combination with modern sequencing approaches continues to provide an invaluable resource in attempts to complete the functional annotation of the genome (Arnold et al., 2011; Brown et al., 2013; Gondo et al., 2010; Kile et al., 2003; Oliver and Davies, 2012; Probst and Justice, 2010).
In order to complete the functional annotation (based on BLAST) with protein domain information, InterproScan [ 52] was run (based on the longest unigene's ORF) and GO terms associated with protein domains were merged with the GO terms kept at the annotation step.
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Before randomisation, and three weeks after completion of docetaxel, patients completed the Functional Assessment of Cancer Therapy-Breast (FACT-B) questionnaire (version 3) and the Rotterdam Symptom Checklist (RSCL) [ 20, 21].
The study presented here completes the functional testing of all known missense variants in the C-terminal region of the BRCA1 protein using transcriptional assays5 and provides an extensive analysis of these variants using VarCall, a computational tool to predict the likelihood of pathogenicity6 given the results from functional assays.
This article contain comprehensive data of completing the functional, complementary unified information model, based on the technology of building information modelling for creation city environment through the whole lifecycle of the building.
Participants: Forty individuals with stroke (IWS group) completed the functional walking handicap survey, 10 of whom agreed (with 10 age-matched controls) to enroll in a study of of the Hmax:Mmax ratio in soleus during walking.
After this examination, all subjects completed the functional testing, consisting of the Functional Movement Screen (FMS) and the Lower Quarter Y Balance Test (YBT-LQ), by an experienced tester who was blinded to the results of the clinical examination.
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