This giraffe has large dark patches that usually have complete margins, but may also have sharp edges.
51 Another study at the VAMC in Houston, TX reported an increased percentage of complete, margin-negative resections (P<0.05) and number of lymph nodes removed during surgery (P<0.01) after establishing a minimally invasive CRC program.
While this work is relevant to the treatment and imaging of receptor-positive breast cancer as well, TNBCs represent a subset of invasive breast cancers whose lack of receptor targets for hormonal therapy confer an even greater dependency upon complete, margin-free surgical resection for patient survival.
A major strength of the present study is the inclusion of patients with solitary CRLM only, who were operated with complete margins (R0) to create an homogenous group of patients.
While various techniques have been used to achieve complete histologic margin control, such as permanent section total peripheral margin control and Mohs micrographic surgery, no prospective randomized data are available to make specific recommendations 4. The nonsurgical options for treatment of MIS include radiotherapy, cryotherapy, laser, and electrodessication and curettage.
BCS, breast-conserving surgery Several authors have described a technique of "complete cavity margin re-excision" for comprehensive evaluation of the surgical resection margins at the time of BCS [ 23, 27, 30, 34, 43].
In 2004, Keskek et al [ 43] reported finding positive disease in "complete cavity margin excision" specimens in 4.3% (13/303) of patients with initial negative margins on the "initial tumour excision".
Although the "complete cavity margin re-excision" technique seems ideal for achieving the most thorough assessment of the surgical resection margins, it significantly increases the overall volume of tissue removed from the affected breast, it is limited by breast size, and it frequently leads to very suboptimal cosmetic results.
MARLA performs all tasks related to planning the fuel shuffle, including the optimisation of the fuel movement schedule, a complete shutdown margin analysis of all intermediate core configurations using the licensing-grade SIMULATE-3 nodal code, and generation of the official Fuel Movement Checklist used by the crane operators during core alterations.
The extent of disease seemed to have some advantages to secure complete resection margin via surgical treatment (P = 0.066).
