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DREs as well other sites for early growth response (EGR), E2F, nuclear respiratory factor 1 (nuclearnucleareceptoror subfamily 2 factors (NR2F/COUP-TF) and peroxisome proliferator-activated receptor (PPAR) were over-represented within AhR enriched regions (Table 3; complete list of over-represented TFBS are provided in Additional Files 6 and 7).
However, we also demonstrated that genes represented by network peripherals-B tend to perform higher-level biological processes (Annex S2 contains complete list of over-represented GO biological processes).
The complete list of over-represented GO terms and predicted functional interactions are shown in Supplementary Table 9 and Supplementary Figure 5, respectively.
Complete lists of over-represented motifs and their enrichment folds are provided as Additional file 3.
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Table SI1 shows the complete list of genes in the overlap and lists the fold over- and under-expression values observed.
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