Sentence examples for complete deficiency of from inspiring English sources

Diabetes mellitus (DM) is characterized by either complete deficiency of insulin secretion as in type 1 DM(T1DM) or decompensation of the pancreatic β-cells in type 2 DM(T2DM).

The disease is an excellent candidate for gene replacement therapy as the majority of mutations have been shown to lead to a complete deficiency of the secreted protein in the retinal structures.

Prolonged drinking that interferes with an adequate diet may lead to Wernicke disease, which results from an acute complete deficiency of thiamin (vitamin B1) and is marked by a clouding of consciousness and abnormal eye movements.

An ultrasound scan confirmed complete deficiency of the patella tendon.

T-B+NK+ severe combined immunodeficiency caused by complete deficiency of the CD3zeta subunit of the T-cell antigen receptor complex.

Dectin-1 is the main β-glucan receptor, and patients with a complete deficiency of either dectin-1 or its adaptor molecule CARD9 display persistent mucosal infections with Candida albicans.

Complement activation mediates inflammation and tissue damage in autoimmune diseases, but also has a protective role, as complete deficiencies of CP components are associated with SLE [ 2, 3].

Bernard Shaw: "Shakespeare's weakness lies in his complete deficiency in that highest sphere of thought in which poetry embraces religion, philosophy, morality.

To circumvent the embryonic lethality of a complete deficiency in insulin-like growth factor 1 (IGF-1), we generated mice homozygous for a site-specific insertional event that created a mutant IGF-1 allele (igf1m).

There was also a strong reduction of the steady state levels of individual respiratory chain subunits and an almost complete deficiency in subunit e (Su e) of the F1FO-ATP synthase.

For Zfp36L1 in mouse, we have recently shown that its complete deficiency leads to universal intrauterine death of the KO embryos, usually at about embryonic day 9 11 [ 55].