Sentence examples for complete complementarity between from inspiring English sources
Translational suppression and mRNA degradation, modes by which mammalian miRNAs regulate gene expression, do not require complete complementarity between the miRNA and target.
Lack of complete complementarity between the two surfaces ensures the separation of oxidized ferredoxin and initiation of a new cycle.
In contrast, synthetic siRNA specificity is dependent on complete complementarity between the siRNA sequence and the target mRNA [ 12, 17].
Complete complementarity between the guide strand and the target mRNA leads to catalytic cleavage of the mRNA and suppresses gene expression [ 1].
In mammals, complete complementarity between miRNA and MRE is rare, since a minimal 6-bp match of nucleotides 2 8 at the 5′ end of miRNA (known as the seed region) is sufficient for functionality [13].
There was complete complementarity between the seed region of miR-128-2 miR-128-2 miR-128-292–2598 nucleotide) and ABCA1 3′UTR (34–40 nucleotidewith andew supplementABCG1airing sites at the 34 40 of miR-128-2.
Perfect complementarity between the miRNA and the 3′-UTR of the target transcript leads to degradation of the mRNA, whereas partial complementarity results in inhibition of translation.
Complete complementarity was found between the 2 7 nt (hexamer) of seed region of miR-128-2 miR-128-2 miR-128-2R α (from 3804 to 3810 nt).
In this study a simple sequence homology search indicated that the inserts identified through the two different selection assays did not recognise any sequences within the human transcriptome with complete complementarity and instead recognised between 7 and 20 different targets, using the criteria of 14 bases of contiguous homology.
A notable difference between asRNAs and sRNAs is that asRNAs share complete complementarity with their mRNA targets, whereas the trans-encoded sRNAs have much shorter complementary regions, and different sequences within a sRNA may bind different mRNA targets.
The regulatory process occurs posttranscriptionally and involves miRNA interaction with a target site in the mRNA that has partial or complete complementarity to the miRNA.
