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Follow-up was complete and outcome had been determined for all patients by the end of the study (31 December 2003).
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In the primary analysis, a complete case approach was adopted, where complete cost and outcome data (either HAQ/QALYs based on the EQ-5D) was required.
We enrolled these 405 patients in the study and compiled their complete treatment and outcome information.
That is, observations were included in analyses 1-6 only where complete cost and outcome data were available (see Figure 1).
They also need to elucidate more clearly the role of delirium and cognitive dysfunction on recovery and indeed on patients' ability to complete clinical and outcome questionnaires.
The PrediCTS cohort enrolled 1107 participants at baseline; 711 (64.2%) had complete exposure and outcome data at follow-up, and did not have prevalent CTS at baseline (figure 2).
The completeness of data within each of those databases is also unclear; investigators might have excluded those without complete exposure and outcome data from analyses.
Assuming that 75% of these women would agree to participate (29,000) and that complete ultrasound and outcome data would be available for 80% of pregnancies, the study would have a projected sample size of 23,000.
Within the analysis sample with complete exposure and outcome data, there were few additional missing values for covariates (n = 17 and n = 16, respectively, for analyses of rapid growth and BMI at 14 months).
The construction and rehabilitation, which included new wiring and plumbing, took nearly two years to complete and the outcome was subtly modern and painstakingly simple.
Complete and accurate outcome data were obtained through direct linkage to the provincial cancer registry.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com