To be a self-replicator, a molecule has to replicate both its exact and complementary copy because replication is complementary (the unit of replication is a pair of complementary sequences).
We used two complementary approaches to investigate replicated patterns of potentially adaptive genetic differentiation along multiple altitudinal gradients.
First, it is assumed that proto-adapters with complementary anticodons when replicating, form intermediary double stranded helices.
These results were replicated in a complementary analysis using only completers (between-group effects: QOLI – p = 0.13, SoC – p = 0.07).
All hybridizations involved a fluorescently-labeled synthetic oligonucleotide that was complementary to a positive control probe, which was replicated for more than 4,000 spots scattered in different zones of each sub-array.
Even if these results need to be replicated, cognitive remediation appears to be a new therapeutic tool, complementary to classical approaches used in childhood psychiatric disorders.
Constraints of cell culture and mouse models mean that there is a need for a complementary model that can replicate the complex in vivo milieu that regulates apolipoprotein and lipoprotein biology.
The book inspired the collaboration between Crick and Watson and led to the identification of genetic information as the sequence of bases in DNA, replicating via complementary base-base recognition.
The coatings were replicated on PMMA substrates with use of a pair of nickel molds containing complementary surface patterns of submicron-sized pillars or pits in a cubic grid.
