Sentence examples for complementary interface from inspiring English sources
As a whole, these results underscore the discriminating nature of the spaces occupied by the 2Nap groups in which size, orientation and chemical makeup of the modifications are all essential to forming the complementary interface between SL1067 and IL-1α.
They also provide evidence that, in spite of the substantial hydrophobicity of the 2Nap moiety, this modification significantly contributes to the binding energy and is capable of forming a highly complementary interface with the target protein.
The sense of audition used as a complementary interface involves several issues which have been identified such as the rhythm and intensity.
As a complementary interface for searching MEDLINE, PubMed (http://www.pubmed.gov) is a likely first choice for people seeking to monitor medical research on a given topic.
The native complex of T25 has a hydrophobic interface with a complementary shape, and that of 1ewy has a modestly electrostatic and shape complementary interface.
To display an overall measure of the interaction frequencies of each amino acid with all the residues of the complementary interface, we calculated the preferences of amino acids in three kinds of interfaces, including TCR-pMHC, Ag-Ab, and protein-protein interfaces.
Both interactions exhibit properties characteristic of antibody-antigen interactions: high affinity, exquisite specificity contributed by a small number of functional hotspot residues, and the size and properties of the complementary interfaces.
Despite a wealth of available structural data of complementary interfaces between proteins and domains, our knowledge remains largely descriptive and only a few generalizable patterns of protein and domain interfaces exist [ 12].
Such a precise pattern of alternating complementary interfaces was not observed in other four-helical bundles, and is likely to be specifically required for the precise architecture of the Kinesin-5 bipolar minifilament.
Computational tools to predict protein protein docking that would allow a rational approach to design novel complementary interfaces are being developed and, although still error-prone [ 13], they may increasingly guide and accelerate the design of functional interfaces between signalling modules.
If we had proposed that this segment of aff4 functions to bind CDK9, we suspect the reviewers would have noted our naïveté about an interaction of a 20-residue helix between molecules in one of 3 crystal complexes that makes a non-complementary interface and contributes less than one kcal per mole to the affinity.
