While van Fraassen's (2008) does not take a position on pluralism vs. monism (and as an empiricist and antirealist van Fraassen would not have to), its emphasis on the partiality and perspective dependence of measurement provides a complementary point of entry to such diversity.
Given their complementary mechanism of action, entry inhibitors inhibit viral infection in a synergistic manner in combination with DAAs both in cell culture models and in human liver-chimeric uPA/SCID mice.
Moreover, this in vitro technology is unlikely to replace animal models of disease, but as has already been shown, provides a complementary tool, and an entry point in identifying novel pathogenic mechanisms that can subsequently be modelled in vivo using animal models.
10 12 21 By acting through a complementary mechanism of action (MOA), entry inhibitors may synergistically act with SOC.
The barrier to entry is in finding complementary roles for new players beyond the first two or three.
The recipient expression vector contains two BsaI restriction sites complementary with the restriction sites from the entry clone (Fig 1, plasmid B).
Polyamide nucleic acids (PNAs) are DNA protein chimeric molecules that can be designed with modifications so as to allow good cell entry and high affinity binding to complementary RNA.
However, we show here characteristic differences in the architecture of actin and septin enrichment at the site of bacterial entry, strongly suggesting distinct and probably complementary roles for actin and septin in the process of entry.
In addition, the indexing of PubChem and ChemSpider by Google has become complementary and transformative because over 50 million aggregated databases entries (including the chemicalize.org archive) can now be checked for an InChIKey match [12].
A promising antiviral target complementary to targets of SOC and DAAs is viral cell entry.
This provides the driving force for fine tuning host-guest interactions at the molecular level and constitutes an entry toward subtle discrimination of different chemicals (e.g. complementary fertilizers, synergistic drugs) during their sequential release.
