Exact(1)
For instance, in tissues from brain, eye or lung, the values for AT-less and AT-spike promoters appear to exhibit a relative complementarity to those from muscle, whereas the number of CG-spike promoters remains proportional to their relative values.
Similar(59)
However, those CODEMIRs with high complementarity to the ICAM-1 mRNA all contained a region of at least 5 contiguous G nucleotides, a feature that is known to be detrimental to siRNA activity [ 8].
Based on our results and those studies, we designed a target sequence with six tandem repeats with perfect complementarity to the mature strand of the miR122 duplex.
The gRNA showed perfect complementarity over 44 nucleotides with the alternative transcript and no significant complementarity to the fully edited ND9 transcript.
TargetScan mainly depends on perfect complementarity to the seed region of miRNA and then extends to complementarity outside the region.
In addition, for most targets, 5′ dominant complementarity to the seed region or incomplete complementarity to 5′ and 3′ (3′UTR compensatory) occurs, resulting in translational suppression [11,12].
One such prediction algorithm, TargetScan requires perfect complementarity to the seed region of miRNA and extends these regions to account for complementarity outside the region.
ASOs bind with sequence complementarity to the mature miRNA to disrupt binding to mRNA targets.
Subsequently, this protein-RNA complex interacts with mRNAs with high complementarity to the miRNA.
56 Consistent with this notion, the 3′ UTRs of housekeeping genes in animals are substantially shorter compared to those of other genes, plausibly avoiding fortuitous complementarity to a plethora of miRNAs they are confronted with in the cells.
The csRNAs of S. pneumoniae and those characterized or predicted in this work show complementarity to translation initiation regions (TIR).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com