Depending on the degree of sequence complementarity, this interaction can mediate either translational repression or mRNA degradation.
Additional comparative assessments in terms of shape complementarity and interaction energies at the interfacial region of GGA3 SAR1 protein complex were also pursued to evaluate our predictions further.
66 The putative low-energy docked conformation of the host parasite protein pair, thus obtained, was probed in terms of surface complementarity and interaction energy of the complex.
DOI: http://dx.doi.org/10.7554/eLife.06866.026 We used the ClusPro server (http://cluspro.bu.edu/login.php) to produce an ensemble of molecular docking models of the BH PTEN complex based on shape complementarity and interaction surface characteristics.
MEGADOCK evaluates each docking pose based on three types of score function, i.e., shape complementarity, electrostatic interactions, and the desolvation free energy.
As we will see later for the KLKs, natural inhibitors of proteases often bind directly to the active site, exploiting some degree of complementarity at the interaction surface [88 90].
Fit of shape and complementarity of electrostatic interactions are derived as significant determinants of molecular recognition of 15d-PGJ2.
CDR3L peptide was directly demonstrated to bind hPrP, confirming the role of hydropathic complementarity in antigen antibody interactions.
Complementarity in lectin glycan interactions in situ is assumed to involve spatial features in both the lectin and the glycan, giving a functional meaning to structural aspects of the lectin beyond its carbohydrate-binding site.
Substrate recognition by the basic protrusion motif involves both shape complementarity and specific interactions between residues within the motif.
