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Using a battery of in vitro assays including: traditional diagnostic hemolytic assays involving sheep and rabbit erythrocytes, ELISAs and flow cytometry, we show that HPG modified RBCs at certain concentrations and molecular weights activate complement via the alternative pathway.
They consequently inhibit the activation of complement via the alternative pathway.
Instead the IgG1 isotype, which does not activate complement via the classical pathway, dominates [27] as shown also by the lack of C1q in the deposits (present study).
The African trypanosome Trypanosoma brucei is covered with a dense layer of Variant Surface Glycoprotein (VSG), which protects it from lysis by host complement via the alternative pathway in the mammalian bloodstream.
They have opsonic properties and are able to activate complement via the lectin pathway.
CRP activates complement via the classical pathway and thereby contributes to the lysis and removal of damaged myocardial cells [ 3].
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These observations fit with a broader theme in economic history which argues that economic and political competition are key complements via the forces unleashed in "open access" orders (North et al. 2009).
These BbCRASPs are differentially expressed and are postulated to confer defense against host-derived complements via specific interaction with FH family proteins [16], [17], [31], [32].
Putative shortened stop codons were already found in other species and are thought to be complemented via post-transcriptional polyadenylation [ 37].
For instance, unlike F1, P. putida W619 was unable to metabolize toluene or TCE, a property that could be complemented via acquisition of the pTOM plasmid of Burkholderia cepacia BU61 (Taghavi et al., 2005; Weyens et al., 2009;).
ABP activated the human complement system via the alternative pathway in human serum.
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