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To circumvent the limitations and complement the capacities of current model systems, we developed a conditionally immortalized urothelial cell line derived from H-2Kb-tsA58 mice.
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Social care of the future will be a professional vocation in which care workers have the freedom and responsibility to provide appropriate supports to strengthen and complement the capacity of the client and her networks – a rewarding career indeed.
To determine whether M. leprae sonicate is a direct activator of human complement, we tested the capacity of M. leprae to induce complement consumption in normal human serum (NHS).
After incubation of J774A.1 cells with M. tuberculosis H37Rv, H37Δ Rv0561c, and H37Δ Rv0561c complemented with pNIP40b Rv0561c, the capacity of each of these strains to infect and survive in the J774A.1 cells was analyzed.
The essential role of properdin in complement activation was demonstrated by the capacity of an anti-properdin monoclonal antibody to inhibit activation of the alternative pathway.
It was also aimed to show that the labeling did not modify the complement activation capacity of the nanoparticles which are designed as drug carriers for the in vivo delivery of siRNA.
To quantify the capacity of MA4265 to complement the icd mutation, growth in liquid medium was monitored.
To address this question, we decided to analyse: 1) which complement pathways are activated by T. cruzi using strains isolated from different hosts, 2) the capacity of these strains to resist the complement-mediated killing at nearly physiological conditions, and 3) whether the complement system could limit or control T. cruzi invasion of eukaryotic cells.
To demonstrate the functionality of its Fc-region, the capacity of IGN311 to mediate complement dependent cytotoxicity (CDC) against human breast cancer cells was evaluated.
Mutation of the Cdc27Nterm dimer interface destabilises the protein, disrupts dimerisation in solution, and abolishes the capacity of E. cuniculi Cdc27 to complement Saccharomyces cerevisiae Cdc27 in vivo.
This property is based on the capacity of the VN fragment to complement with the C-terminal fragment of Cerulean, producing a Venus-like fluorescent signal.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com