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The diagnosis is established through evaluation of family history and clinical manifestations, complement testing, and genetics analysis.
15, 16 HAE-C1-INH can be diagnosed with complement testing; molecular genetics analysis is helpful in uncertain cases; it is an important tool in prenatal diagnostics.
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The results of a coagulation test, thyroid function test, complement test and antinuclear antibody test were normal.
Other complement tests were normal, including C3, C4, classical and alternative pathway activity, Factor H and Factor I levels.
Inhibitor assay and complement test in E. coli revealed that A. thaliana gyrases are involved in organellar genome replication (Wall et al. 2004).
The use of human complement when testing the bactericidal activity of vaccine-induced antibodies against serum resistant gonococci is also important.
This human serum was used as a source of complement to test for complement-mediated target cell lysis.
This human plasma was used as a source of complement to test for complement-mediated target cell lysis before and after knockdown in CD46, CD55 and CD59 expression by siRNA in the presence of trastuzumab.
Serological tests including the serum agglutination test (SAT or STAT), anti-human globulin test (Coombs test), complement fixation test (CFT) and Enzyme-linked Immunosorbent Assay (ELISA), therefore, are indispensable for an accurate diagnosis [ 9].
Antibody response was assessed by classical tests (Rose Bengal test, complement fixation test (CFT)) in comparison with other diagnostic tests (indirect ELISA (iELISA), competitive ELISA (cELISA), fluorescence polarization assay (FPA), immunocapture test (ICT)).
As we discussed in "Material and Methods," this information has to be complemented with testing the homogeneity of the bands.
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