Sentence examples similar to complement pathway activation status from inspiring English sources

Burington, B. et al. CD40 pathway activation status predicts response to CD40 therapy in diffuse large B cell lymphoma.

Sprong T, Roos D, Weemaes C, Neeleman C, Geesing CL, Mollnes TE, et al. Deficient alternative complement pathway activation due to factor D deficiency by 2 novel mutations in the complement factor D gene in a family with meningococcal infections.

C3 was considered as a significant feature of complement pathway activation because of its key role in all complement activation pathways (Jones et al., 2013).

This binding results in tightly controlled classical complement pathway activation, leading to the production of C4b.

FLIPr at 1 μM reduced the complement classical pathway activation to ~56% and to ~26% when used at 5 μM (Fig. 3 g).

Atypical haemolytic-uraemic syndrome (aHUS) is a disease of uncontrolled complement alternative pathway activation.

Our study highlights the status of both complement classic and alternative pathway activation in the pathogenesis of renal TMA in lupus nephritis.

To complement the mutation data, and for a better overview of the activation status of the PI3K pathway, we investigated a set of previously published GSs.

Activation of the complement pathway results in enhanced cleavage of C3 to C3a and C3b (reviewed in ref. 16) (Fig. 1a).

Within the ocular microenvironment the alternative complement pathway exhibits low levels of constitutive activation to ensure the intermittent probing of host self cells, which express inhibitors of complement for protection from activation.

An additional intrinsic characteristic of antigen-specific antibody is the ability to mediate activation of the complement pathway.