Sentence examples for complement disorders from inspiring English sources

To confirm our main result, we used a multicentre French database to identify adult with aHUS referred between 2000 and 2008 to the laboratory of immunology at Hôpital Européen Georges Pompidou (Paris, France), the French reference centre for the evaluation of complement disorders in human diseases.

Again, in most complement-related disorders, the relative contribution of the AP and CP is not known.

Although not a complement-mediated disorder, HAE is caused by lack or deficiency of endogenous C1-INH and replacement therapy has been well studied.

This represents the type of data that can be useful in the formulation of pathogenetic hypotheses because the role of complement in these disorders is under-explored.

Evidence for and against therapeutic modulation of specific complement pathways in these disorders is presented.

Disorders in complement regulation are a major cause of atypical haemolytic uraemic syndrome (aHUS).

This dynamic and efficient perspective on regional changes in brain disorders can complement the histopathological information provided by neuropathological studies.

The rates reported in the DGH sample are consistent with data from community surveys of patients meeting criteria for mental disorders and complement such data when it comes to planning for paediatric MHS.

This patient shows activity in both CCP and CAP, with decreased levels of early components of each pathway namely C4 and factor B. Since multiple components are decreased through consumption in both the classic and alternative complement pathways, an acquired disorder rather than genetic seems likely and genetic testing for an inherited disorder was not performed.

These findings could propose that TMD conditions in pre-pubertal age mainly are of muscular origin and then with age are complemented with intra-capsular disorders.

Atypical HUS designates a primary disease due to a disorder in complement alternative pathway regulation.