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complement dependent cytotoxicity.
Concentrations of the complement systems' components (CS) determine the patients' ability to fight cancer by complement dependent cytotoxicity (CDC).
Increasing concentrations of complement system components resulted in increased efficacy of the ovarian cancer cells killing as complement dependent cytotoxicity (CDC).
Mechanisms of action include: (I) inhibition of growth by steric inhibition of receptors' dimerization; (II) antibody-dependent cell-mediated cytotoxicity (ADCC); (III) complement dependent cytotoxicity (CDC) [8 11].
Virulent leptospires displayed complement resistance in human serum and whole blood while in-vitro attenuated non-virulent leptospires were rapidly killed in a complement dependent manner.
Furthermore, h357 IgG1 possesses the ability to mediate antibody-dependent cell-mediated cytotoxicity and complement dependent cytotoxicity upon binding to cells bearing the transmembrane form of TNF-α.
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This can be attributed partially to the antibody-mediated complement-dependent cytotoxicity (CDC) or ADCC.
Complement-dependent cytotoxicity (CDC) is a potent promoter of tumor clearance during monoclonal antibody therapy.
Furthermore, it could kill CD20 positive Daudi and Raji cells by complement-dependent cytotoxicity.
Furthermore, IgGA mediates greater complement-dependent cytotoxicity than IgG1 or IgA antibodies.
Complement activation by the Fc portion of the antibody results in complement-dependent cytotoxicity.
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