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Cancer and the complement cascade.
Stevens, B. et al. The classical complement cascade mediates CNS synapse elimination.
This initiates a molecular chain reaction known as the complement cascade.
We think it might be fractalkine [and] we also suspect that the complement cascade proteins are involved".
Heparin is a naturally occurring polysaccharide known to interact with complement proteins and regulate multiple steps in the complement cascade.
Upregulation of the majority of the complement cascade was observed including the membrane attack complex components and complement inhibitors.
Human complement factor H FHH), an abundant 155-kDa plasma glycoprotein with 40 disulphide bonds, regulates the alternative-pathway complement cascade.
The anti-C5 monoclonal antibody Eculizumab has been successfully utilized for aHUS treatment, being able to block the complement cascade.
Presence of specific IgG or IgM, however, results in strong activation of the complement cascade via the classical pathway11.
Endothelial and leukocyte responses are involved in tissue injury, orchestrated primarily by the complement cascade.
They directly neutralize viral infections or lyse pathogens by activating the complement cascade.
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