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We compiled gene expression data from 1,082 published microarray experiments under various cellular conditions.
Using these cell lines we created a taxane-anthracycline-sensitive reference profile for sensitive/resistant cell lines (log IC50) < −1) and compiled gene expression centroids for each.
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One such project, Webb says, has researchers compiling gene expression data from more than 2,500 ovarian tumor samples and using several computer algorithms to predict whether any existing drugs could potentially treat ovarian cancer broadly or treat specific molecular subtypes.
Compiling gene expression data derived from micro-array analysis [ 19- 21], we determine Pearson's correlation coeffcients r P of each interaction (see Materials and Methods).
The need for systematically compiling gene-expression data in one place is obvious from previous efforts.
The data files from the ABI Mouse Genome Survey microarray v.1.0 were processed using J-Express Pro to filter and normalize the data from each hybridization and compile gene expression profile matrix (gene by sample) datasets for further analysis.
In order to achieve a deeper understanding of the evolutionary divergence between human and mouse in a higher order, we compiled two gene expression matrixes, which included 6,200 pairs of one-to-one orthologs across 29 homologous tissues for human and mouse.
We compiled available gene expression data from the Stanford Microarray Database [ 47], a total of 1,082 published microarray experiments for 6,260 genes in various cellular conditions.
We compiled the gene expression data for a total of 506 samples, after averaging the expression values over the technical replicates in the lung dataset and in NCI60 cell lines.
Lists of genes affected by FGF inhibition were compiled by comparing gene expression changes in dnFGFR4 injected embryos versus control embryos.
By following the above criteria, we compiled 3,030 microarray gene expression profiles across a variety of human tissues (Table 1).
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