To explore a possible connection between A. thaliana STSP and FBX pseudogenes and the stress/pathogen responses, we examined the expression correlations of all A. thaliana FBX genes in the full compilation of expression microarray datasets available at NASCArrays.
Here, we have attempted an analysis of a compilation of expression profiles to gain insight into the hormonal regulation of liver gene expression.
Manual compilation of gene expression data, which can be a painstaking process, followed by a consensus expression status determination for specific locations and conditions, can be a reliable way of making use of the existing data to predict gene expression patterns.
The Broad-Novartis Cancer Cell Line Encyclopedia (CCLE) contains a compilation of gene expression, chromosomal copy number, and massively parallel sequencing data from 947 human cancer cell lines that are used as models for various tumor types [ 7].
As the cytotoxic effect of I3C and bortezomib was rapid (24 h), a compilation of gene expression profiles from earlier time points may provide more insight into the mechanism of these combined agents in ovarian cancer, similar to the study performed with I3C in prostate cancer cells at three time points (Li et al, 2003).
Compilation of gene expression responses in M. truncatula wild type A17 (WT), nfp-1 (NFP), dmi3 (DMI3), nsp1-1 (NSP1), and ram1-1 (roots plantlet roots challenged with 10−8 M sMyc-LCOs (sMyc), 10−7 M nsMyc-LCOs (nsMyc), a mixture of 10−8 M sMyc- and 10−7 M nsMyc-LCOs (s/nsMyc), and 10−8 M Nod-LCOs (Nod).
The first is an inventory of the proteins modified by HNE, and the second is a compilation of the gene expression changes determined by microarray analysis.
A compilation of all gene expression data is available as Additional file 1 (Table S1), and will be discussed in detail in the subsequent chapters.
The outline of the study was the following: After compilation of the tissue expression data sets, we first examined their overall similarity.
Here we analyzed a compilation of rat liver expression profiles from experiments designed to study gender and hormone actions in order to provide novel insight into the mechanisms of action of specific hormones.
