We find that the transcriptional repressors KNIRPS, KRUPPEL and GIANT are able to restrict reporter gene expression to the posterior abdominal segments, using different molecular mechanisms including short-range repression and competitive binding.
These results suggest that different miRNA combination patterns can produce coordinate action, which increases the repressive effect of miRNAs on VEGF translation, or competitive action, which failed to generate further repression of VEGF translation.
Nothing is more likely to drive a dictatorship to extremes of repression than the threat of a competitive election.
The lack of CF repression renders the postsynaptic membrane more receptive to the competitive input that invades the proximal dendritic domain.
We are still an archaic country, incapable of creating a competitive, attractive Russia, so we opt for the forces of religious-political repression.
In the case of PG-1, repression of tobacco anthocyanin production appears to be the result of competitive inhibition of one or more tobacco myb proteins.
We propose that proteins of this group act as auxin-independent competitive inhibitors of ARF dimerization, inhibiting both potentiation (via ARF-ARF dimerization) and repression (via ARF-Aux/IAA dimerization) of the auxin response.
Strikingly, SB415286, a potent and selective cell-permeant, ATP-competitive inhibitor of GSK3α and GSK3β [ 28, 29], also caused strong repression of the AA-induced phosphorylation of p70S6K1 and S6.
Competitive inhibition of ANRIL binding by expression of an antisense sequence impairs CBX7-mediated repression of the CDKN2A locus and causes a concomitant shortening of cellular life span.
To this and another question, Mr. Putin said that Russia should have a competitive electoral system and that the lack of support for the opposition was not because of repression but their own actions.
