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A health care intervention is considered to be "cost-saving" when it costs less but provides incremental benefit relative to a competing intervention; "highly cost-effective" when it costs less than the GDP per capita; and "cost-effective" when it is between one and three times a country's GDP per capita [49].
NMA enables researchers to obtain the relative efficacy of a particular intervention versus any competing intervention even when direct evidence is not present, via a common comparator.
When all data are expressed in money, it is possible to calculate the likelihood that an intervention is cost-effective in relation to a competing intervention.
In ranking the competing intervention options, quantitative and qualitative approaches can be used; Jones et al. (2010) highlighted a particular set of priority-setting criteria used by military working groups to address injury prevention.
Weaknesses include those shared with all non-randomised, retrospective observational database studies 29 and the aforementioned inherent weakness of having a competing intervention (changes in coding guidelines) in our analysis.
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How might researchers go about reviewing the evidence when they are faced with multiple or indeed competing interventions addressing the same problem?
We do not question the value of the randomized design of 'treatment' trials for comparing competing interventions (treatments), but we have serious concerns about the use of randomization in the evaluation of a diagnostic test, such as CT.
The funding of the intervention is vital and given the scarce resources and competing interventions (malaria and non-malaria related) countries may recognise the advantages of introducing IPTi but struggle to secure the funds.
Healthcare decision-making requires comparisons of all relevant competing interventions.
For cost-effectiveness evaluations of competing interventions that aim to improve survival, differences in expected survival between the competing interventions are of interest.
3 Sound decision making requires comparisons of all available, relevant competing interventions.
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CEO of Professional Science Editing for Scientists @ prosciediting.com