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DOI: http://dx.doi.org/10.7554/eLife.11611.012 The prolonged competition observed in slow-exchange strains allowed us to ask whether late-arriving factors such as septins are recruited to one or more of the competing clusters.
Given the costs of the various reductions and their order to be evaluated in, determined in the first two steps, the algorithm attempts to cluster those contexts closest to one another, with the enforced constraints that only competing clusters of the same composition are compared.
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From the NMI scores, the proposed algorithm is clearly superior to the competing clustering algorithms.
Thus, the simplest hypothesis is that elimination of excess clusters reflects the depletion of polarity factors from losing clusters as they are acquired by a competing cluster.
Thus, the disappearance of a cluster could not be unambiguously attributed to the presence of a competing cluster in the same cell.
These findings imply that it is the presence of a competing cluster that promotes the dissolution of other clusters in the same cell.
In order to optimize the enniatin production in this host, several cultivation conditions and the deletion of potential competing gene clusters for native secondary metabolites were addressed.
The analysis is complex due to competing events, clustering, multiple timescales and time-dependent period and intervention variables.
Supermarkets compete with clusters of kiranas, which together can offer most of the same products.
In the case of heterotypic clusters, competing factors can bind even to very well determined motifs that overlap.
Our statistical test for determining if the addition of an extra sub-type significantly increases the observed heterogeneity signal used a reference distribution in which the differences in the optimal values of D* for the competing numbers of clusters were calculated repeatedly from datasets in which the subject labels were permuted.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com