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The kinetic model emphasizes the relevant role of MTBE in the reaction, which competes for the active centers with the methanol.
The order on methane and steam obtained through power-law model were 0.94 and −0.16, respectively, where the negative order on steam clearly indicates that steam competes for the active sites which are the precursor for methane decomposition [22], and Model 7 representing a single-site was consistent with this finding (Fig. 8).
In fact, IDE is better classified as a competitive substrate; it appears to inhibit because it competes for the active site but then reacts only slowly.
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However, acetaldehyde also produces surface carboxylate species which compete for the active sites and make the condensation process less efficient.
At submicromolar concentrations of L-Asn, as occurs in the blood for the treatment of ALL, L-Gln is the most abundant substrate competing for the active site, and so the enzyme begins to present nH = 1.0, which features Michaelis Menten kinetics.
Such behavior is due to the interaction between the biosorbent surface and added solutes which may compete for the active sites and consequently block the diazinon biosorption.
In this model, pEndos and CDK-phosphorylated substrates compete for the active site of PP2A-B55.
Second, we consider the case where two substrates may be simultaneously competing for the active site of a single enzyme.
This is rationalized by the fact that succinate and αKG compete for the active site of PHD2 (Letouze et al., 2013; MacKenzie et al., 2007; Xiao et al., 2012).
This salt is likely to be perturbing these amplifications via Cl-, as this anion is known to compete for the active site of polymerase enzymes more effectively than phosphate, glutamate and acetate [ 41].
The importance of such protease regions which interact with the flaps is implied in studies of developing allosteric inhibitors for HIV-1 protease that do not compete for the active site, where they are targeted as allosteric sites (Lebon and Ledecq 2000; Perryman et al. 2004; Hornak and Simmerling 2007; Yang et al. 2012).
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