Sentence examples for competent viruses from inspiring English sources

The use of replication competent viruses that selectively target and destroy cancer cells has rapidly evolved over the past decade and numerous innovative oncolytic viruses have been created.

Contrary to previous designs to analyze HIV-1 fitness, these replication competent viruses were created in an intact viral genetic background (without deleting or affecting the expression of any viral gene).

Non-cytopathic replication competent viruses of two Sindbis viral strains, TE and 633, were developed using a non-structural protein (nsP) P726S point mutation in order to obtain persistent heterologous gene expression in infected Baby Hamster Kidney (BHK) cells and Chinese Hamster Ovary (CHO) cells.

While it is possible that some HIV controllers may simply be infected with defective viruses [39], most harbor replication competent viruses that lack gross deletions or lethal mutations [40], [41].

As the experiments in this study were performed using replication competent viruses, it was important to determine the extent to which the overall inhibition described could be accounted for by the action of known HIV-1 specific IFNα-inducible proteins tetherin and APOBEC3G.

In this study we were able to identify replication competent viruses, in the absence of any selective pressure against wild type reversion.

These patients are infected by replication competent virus strains.

Whether the proliferating and persisting HIV infected cells we describe harbor replication competent virus is critical to defining their role in perpetuating the infectious virus reservoir.

Antitumor efficacy of a replication competent virus was also increased significantly.

CaGl also resulted in significant anti-tumor efficacy when combined with a replication competent virus (Fig. 5f).

Isolates were minimally passaged in an attempt to ensure isolates reflected the replication competent virus present in vivo [28], [29].