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These effects are likely to be amplified in vivo where the declining pool of replicatively competent cells would be called upon to divide more often to fulfill the needs of tissue regeneration.
Old skeletal muscle loses its regenerative ability due to the failure of satellite cells (muscle stem cells) to divide and generate fusion competent myoblasts and terminally differentiated myofibers in response to muscle injury or attrition [ 1, 2].
These meristematic cells have been prevented from differentiation even if they have lost the capacity to divide suggesting that they were not competent for elongation and differentiation.
Since sterile cells continue to divide during the 6-hr incubation, while mating competent cells do not, the ratio of yEVenus-positive to nonfluorescent cells was converted to a frequency of steriles in the population using a standard curve.
A potentially significant growth-related difference is that differentiation-competent cells attain a higher final cell density; the implication being that they continue to divide for a period of time post-confluence.
To divide?
How to divide the spoils.
I learned to divide".
How to divide it.
They seek to divide Londoners.
Boycotts serve to divide.
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CEO of Professional Science Editing for Scientists @ prosciediting.com