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This truncated form has been shown to be transcriptionally competent to activate a subset of known PGC-1α target genes in brown adipocyte tissue (Zhang et al., 2009).
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To determine which, if any, adult tissues are competent to activate an islet β cell program, we performed an in vivo screen by expressing three β cell "reprogramming factors" in a wide spectrum of tissues.
Origins are licensed to make them competent to activate by the assembly of a prereplication complex during late mitosis and G1 phase.
Taken together, the data suggest that Smo can adopt multiple conformations that allow ciliary trafficking, but only a subset of these are competent to activate the Hh cascade.
Thus, we infer that a portion of Gαo[G203T] can form a competent Fz2-transducing complex, and a portion of overexpressed Gαo[G203T] resides in a free GDP-loaded form that is also competent to activate downstream targets – Ank2 in the context of NMJ formation.
Thus, midbrain neuroepithelium may be more competent to activate Shh expression.
While all cells of the model meristem are in principal able to express WUS, we added a spatial parameter which makes cells that reside closer to the meristem tip more competent to activate WUS expression (Fig. 1B).
LNCaP cells, on the other hand, were competent to activate NF-κB in response to RSV infection.
However, it has been shown that HCT116 cells are fully competent to activate Chk1 when damaged with topoisomerase I inhibitors [ 21] and we have confirmed this in our own laboratory (data not shown).
Seconds later he appeared to activate a suicide bomb.
— no need to activate a skill.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com