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One hypothesized form of disease control is to exclude deer from defined areas [12] which presumes that deer removal will prevent tick life cycle from being completed, thus leading to fewer ticks feeding on woodland rodents, which are the most competent hosts for the pathogen.
Heterogeneities in contact rates between arthropod vectors and hosts are important to vector-borne disease dynamics, because they can result in increased disease transmission if vector blood meals occur more commonly on pathogen-competent hosts.
In addition, it can also facilitate the co-transmission of various competent resistance determinants among different pathogens.
Key proteins in the anti-viral RNA interference (RNAi) pathway, including Ago2 and Dicer-2, are functional in vector mosquitoes and influence the ability of mosquitoes to serve as competent vectors of human virus pathogens [ 1, 25- 27].
It seems likely, in fact, that the prevalence of the repeat families present in the pneumococcal chromosome exemplifies a potential disadvantage of the intrinsically competent lifestyle these three respiratory pathogens have adopted: the risk of acquiring genomic parasites that may cause considerable disruption whilst they remain mobile.
They are also increasingly recognized as pathogens in immuno-competent individuals.
In addition to causing infections in immuno-compromised patients, this group of organisms has been reported to be increasingly recognized as pathogens from immuno-competent individuals as well [ 3, 4].
The concept behind these descriptors is that a minimal set of antigens that induces a competent immune response to a pathogen or neoplasm can be discovered using immunoinformatics, and that administration of these epitopes in the right delivery vehicle and with the correct adjuvant will result in a degree of protection against infection by the pathogen.
Due to climate change and the propagation of competent arthropods worldwide, arboviruses have become pathogens of major medical importance.
Toxoplasma gondii is an obligate intracellular protozoan, belonging to the phylum Apicomplexa and is an important pathogen in both immune competent and immune compromised humans.
T. gondii is an obligate intracellular protozoan, belonging to the phylum Apicomplexa, and is an important pathogen in both immune competent and immune compromised humans.
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