Sentence examples for competent for signalling from inspiring English sources

Clearly, the cells expressing CLN3 remain competent for signalling downstream of Notch.

Finally, we show that proteasome inhibitors can partly rescue the CMG2 protein, which then properly folds, is released from the ER, and targeted to the cell surface where it is competent for signalling.

We conclude that despite asymmetry in the ligand-receptor interaction, both sides are competent for signaling, and appear to signal equally.

Collectively, our results (Text S1) do not support that there is an absolute requirement for cysteine residues in LevQ or LevT to achieve a tertiary structure that is competent for signaling by LevQRST.

In addition, our previous data indicates that the CA-CSF-1R Y561F is equally competent for signaling as it can induce growth factor independence in MCF-10A cells and promote MCF-10A acini growth similar to CA-CSF-1R [8].

Although both full-length and processed forms of the receptor can bind the ligand, only the cleaved form of TLR is competent for signal transduction.

In summary, our study presents a systematic dissection of the Wnt3a-Fz8-CRD complex and identifies sites competent for binding and for signaling in vitro as well as in vivo, providing a model for the modulation of Wnt activity by CRD-related proteins.

We employed a non-immortalized, non-transformed primary fibroblast cell line that is fully competent for IRF3 signaling and is susceptible and permissive to infection by HSV-1.

At some point in this process, RIG-I becomes competent to engage an immune signaling response through an interaction with the adaptor protein MAVS (red), however the determinant step for signaling has not been conclusively demonstrated.

defer.add img); Whistle for signaling for help.

To maintain highest plasticity, C2C12 cells were kept undifferentiated and competent for BMP-induced signalling by subculture conditions that maintained a low density corresponding to approximately 150,000 cells per 182 cm.