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In the present study, we provide evidence that leishmania also produces specific tsRNAs, and that these potential regulatory RNAs are released by the intracellular amastigote stage within bona fide exosomes, competent for delivery to mammalian cells.
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In contrast to Notch1 receptors, S1-resistant Notch2 receptors are fully competent for cell surface delivery and for activation by ligands.
However, Notch1 and Notch2 receptors engineered to resist S1 cleavage exhibit unexpected differences in surface delivery and signaling competence: S1-resistant Notch1 receptors exhibit decreased, but detectable, surface expression and ligand-mediated receptor activation, whereas S1-resistant Notch2 receptors are fully competent for cell surface delivery and for activation by ligands.
Silica-based controlled drug delivery systems are competent for pure sustained-release systems but can be functionalized to response changes in pH, redox potential, temperature, biomolecules, or even magnetism and luminescence [ 31, 32].
PLGA is found to be a promising synthetic polymer for different biomedical applications, including their implications in designing competent drug delivery systems.
Magnetic nanoparticle technology thus offers the potential for selective and competent delivery of therapeutic genes or drugs due to external magnetic fields [97].
"It's for delivery".
"Please allow 4-6 weeks for delivery".
Allow three to seven days for delivery.
Finally, D (for delivery) day.
There was no timetable for delivery.
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